Detalles de la búsqueda
1.
Decoding Complexity in Synthetic Oligonucleotides: Unraveling Coeluting Isobaric Impurity Ions by High Resolution Mass Spectrometry.
Anal Chem;
96(2): 904-909, 2024 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38158374
2.
Comprehensive N-Glycan Mapping using Parallel Reaction Monitoring LC-MS/MS.
Pharm Res;
40(6): 1399-1410, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-36513905
3.
Modern analytics for synthetically derived complex drug substances: NMR, AFFF-MALS, and MS tests for glatiramer acetate.
Anal Bioanal Chem;
407(29): 8647-59, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26458562
4.
Analytical techniques and bioactivity assays to compare the structure and function of filgrastim (granulocyte-colony stimulating factor) therapeutics from different manufacturers.
Anal Bioanal Chem;
406(26): 6559-67, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24264620
5.
Qualitative and quantitative analysis of glutathione and related impurities in pharmaceuticals by qNMR.
J Pharm Biomed Anal;
242: 116010, 2024 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38364345
6.
The Use of Mass Spectrometry in Therapeutic Protein Biologics License Applications: A Retrospective Review Revisited.
J Am Soc Mass Spectrom;
34(11): 2575-2584, 2023 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37843827
7.
Development and validation of a quantitative proton NMR method for the analysis of pregnenolone.
J Pharm Biomed Anal;
222: 115073, 2023 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36206694
8.
Performance Characteristics of Mass Spectrometry-Based Analytical Procedures for Quantitation of Nitrosamines in Pharmaceuticals: Insights from an Inter-laboratory Study.
J Pharm Sci;
112(10): 2685-2695, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37524228
9.
Quality assessment of U.S. marketplace vancomycin for injection products using high-resolution liquid chromatography-mass spectrometry and potency assays.
Antimicrob Agents Chemother;
56(6): 2824-30, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22371900
10.
Tandem mass spectrometric sequence characterization of synthetic thymidine-rich oligonucleotides.
J Mass Spectrom;
57(4): e4819, 2022 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35347805
11.
Detection of possible economically motivated adulterants in heparin sodium and low molecular weight heparins with a colorimetric microplate based assay.
Anal Chem;
83(18): 7102-8, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21819047
12.
Sensitive detection of oversulfated chondroitin sulfate in heparin sodium or crude heparin with a colorimetric microplate based assay.
Anal Chem;
83(9): 3422-30, 2011 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21449571
13.
Aminopyridinecarboxamide-based inhaled IKK-2 inhibitors for asthma and COPD: Structure-activity relationship.
Bioorg Med Chem;
19(3): 1242-55, 2011 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21236687
14.
Characterization of currently marketed heparin products: analysis of molecular weight and heparinase-I digest patterns.
Anal Bioanal Chem;
401(8): 2445-54, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21901459
15.
In Vitro Analysis of N-Nitrosodimethylamine (NDMA) Formation From Ranitidine Under Simulated Gastrointestinal Conditions.
JAMA Netw Open;
4(6): e2118253, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34181009
16.
Expression, purification, and characterization of TYK-2 kinase domain, a member of the Janus kinase family.
Biochem Biophys Res Commun;
396(2): 543-8, 2010 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20435017
17.
Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship.
Bioorg Med Chem;
18(1): 403-14, 2010 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19914076
18.
A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin.
AAPS J;
22(4): 89, 2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32613429
19.
A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal models.
J Pharmacol Exp Ther;
329(1): 14-25, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19168710
20.
Novel tight-binding inhibitory factor-kappaB kinase (IKK-2) inhibitors demonstrate target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation.
J Pharmacol Exp Ther;
330(2): 377-88, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19478133